Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11273907 | 0.99 | SLC6A4 (0.37) | SLC6A4SLC6A3KCNA5SLC6A2KCNH2 | |
| SCHEMBL11282869 | 0.83 | SLC6A3 (0.40) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| Bromide SCHEMBL11277120 | 0.77 | CA2 (0.37) | MAPT | |
| SCHEMBL11252797 | 0.74 | HTR2C (0.41) | MAPTHTR2C | |
| SCHEMBL11256784 | 0.66 | ALDH1A1 (0.41) | SLC6A4SLC6A3SLC6A2MAPT | |
| SCHEMBL27014482 | 0.65 | DRD2 (0.50) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11282109 | 0.59 | CARM1 (0.44) | TP53MAPT | |
| SCHEMBL15828870 | 0.59 | MAPT (0.52) | TP53MAPT | |
| SCHEMBL22411087 | 0.56 | MAP2K1 (0.48) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL9870878 | 0.56 | SLC6A2 (0.58) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002978-B1 | THIAZOLIDINEDIONE-2,4 DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL APPLICATIONS | SYNTHELABO (FR) | 1982-10-06 | — | — | EP | claimed |