Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8123526 | 0.88 | CA2 (0.49) | CA2LMNASMN1; SMN2HTR6CA1 | |
| SCHEMBL438614 | 0.88 | CA2 (0.49) | CA2LMNASMN1; SMN2HTR6CA1 | |
| SCHEMBL7966432 | 0.84 | LMNA (0.61) | CA2LMNASMN1; SMN2CA1CA9 | |
| SCHEMBL17272346 | 0.82 | LMNA (0.45) | CA2LMNASMN1; SMN2HTR6CA1 | |
| SCHEMBL11102654 | 0.79 | LMNA (0.48) | CA2LMNASMN1; SMN2HTR6FFAR1 | |
| SCHEMBL8103835 | 0.77 | LMNA (0.46) | CA2LMNASMN1; SMN2HTR6FFAR1 | |
| SCHEMBL7781985 | 0.77 | LMNA (0.46) | CA2LMNASMN1; SMN2HTR6FFAR1 | |
| SCHEMBL1117923 | 0.77 | CA2 (0.53) | CA2LMNASMN1; SMN2CA1FFAR1 | |
| SCHEMBL1044755 | 0.77 | CA2 (0.53) | CA2LMNASMN1; SMN2HTR6CA1 | |
| SCHEMBL6980879 | 0.77 | CA2 (0.53) | CA2LMNASMN1; SMN2HTR6CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329348-A | ANTIDEPRESSANTS AND PSYCHOSTIMULANTS | CIBA-GEIGY CORPORATION (US) | 1982-05-11 | — | — | US | disclosed |