SCHEMBL11246265

SCHEMBL11246265

CC(=O)c1ccc(-n2cc(C#N)c(=O)[nH]c2=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 1.00
MEN1 O00255 1/20 1.00
L3MBTL1 Q9Y468 1/20 0.65
GAA P10253 1/20 0.49
PGR P06401 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11243353 0.84 KMT2A (0.73) KMT2AMEN1L3MBTL1GAASMN1; SMN2
SCHEMBL11268300 0.82 L3MBTL1 (0.72) KMT2AMEN1L3MBTL1GAASMN1; SMN2
SCHEMBL11254345 0.80 L3MBTL1 (0.68) KMT2AMEN1L3MBTL1GAASMN1; SMN2
SCHEMBL11237480 0.80 L3MBTL1 (0.68) KMT2AMEN1L3MBTL1GAASMN1; SMN2
SCHEMBL11245813 0.80 L3MBTL1 (0.68) KMT2AMEN1L3MBTL1GAASMN1; SMN2
SCHEMBL11248370 0.79 L3MBTL1 (0.67) KMT2AMEN1L3MBTL1GAASMN1; SMN2
SCHEMBL11247073 0.79 L3MBTL1 (0.67) KMT2AMEN1L3MBTL1GAASMN1; SMN2
SCHEMBL11237396 0.79 L3MBTL1 (1.00) KMT2AMEN1L3MBTL1GAASMN1; SMN2
SCHEMBL11248322 0.79 L3MBTL1 (0.67) KMT2AMEN1L3MBTL1GAASMN1; SMN2
SCHEMBL11244000 0.79 L3MBTL1 (0.67) KMT2AMEN1L3MBTL1GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4358591-A BACTERICIDES, FUNGICIDES; PLANT DISEASES ZOECON CORPORATION (US) 1982-11-09 US disclosed
US-4338318-A FUNGICIDE OR BACERICIDE TO TREAT PLANT DISEASES WITH A PHENYL URACIL ZOECON CORPORATION (US) 1982-07-06 US disclosed
US-4307098-A 2-PHENYL-URACIL COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-12-22 US disclosed
US-4297297-A α-Cyano-β-(substituted-anilino)-N-ethoxycarbonylacrylamide intermediates ZOECON CORP. (US) 1981-10-27 US disclosed
US-4266056-A FUNGICIDES, BACTERICIDES ZOECON CORPORATION (US) 1981-05-05 US disclosed