Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PRUNE1 | Q86TP1 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6368700 | 0.79 | KDM4E (0.44) | NPC1MAPTMEN1KMT2ATSHR | |
| SCHEMBL2023829 | 0.79 | ADRA2A (0.50) | MAPTKMT2APOLBLMNAADRA2A | |
| SCHEMBL27633073 | 0.73 | LTA4H (0.46) | RAB9ATSHRPOLBLMNAALDH1A1 | |
| SCHEMBL28904914 | 0.70 | PTGIR (0.64) | ADRA2A | |
| SCHEMBL10055019 | 0.69 | MAPT (0.82) | RAB9ANPC1MAPTL3MBTL1MEN1 | |
| SCHEMBL1844199 | 0.69 | MAPT (0.82) | RAB9ANPC1MAPTL3MBTL1MEN1 | |
| SCHEMBL5669873 | 0.69 | MAPT (0.82) | RAB9ANPC1MAPTL3MBTL1MEN1 | |
| SCHEMBL1179041 | 0.69 | MEP1B (0.43) | RAB9ANPC1ADRA2AADRA1A | |
| SCHEMBL12870230 | 0.69 | APP (0.42) | L3MBTL1TSHREGFRADRA2AALDH1A1 | |
| SCHEMBL1178570 | 0.69 | GSK3B (0.44) | L3MBTL1GAACLK4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315020-A | Oxazoline (trifluoroethyl) amine | SCIENCE UNION ET CIE (FR) | 1982-02-09 | — | — | US | disclosed |
| US-4315019-A | Novel aryltrifluoroethylamines and processes for producing the same | SCIENCE UNION ET CIE (FR) | 1982-02-09 | — | — | US | disclosed |
| US-4267345-A | 2-//PYRROL-2-YL, THIEN-2-YL, OR FUR-2-YL/-ALPHA-TRIFLUOROALKYL-AMINOOXAZOLINES; HYPOTENSIVE AGENTS | SCIENCE UNION ET CIE (FR) | 1981-05-12 | — | — | US | disclosed |