Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10833768 | 0.84 | GABRA1 (0.43) | GABRA1GABRB2POLBGAAMEN1 | |
| SCHEMBL10684859 | 0.81 | GABRA1 (0.52) | GABRA1GABRB2POLBGAAMEN1 | |
| SCHEMBL5097086 | 0.81 | SHBG (0.52) | SHBGMAPTPKMNPSR1KDM4E | |
| SCHEMBL14693998 | 0.77 | GABRA1 (0.45) | GABRA1GABRB2POLBGAAMEN1 | |
| SCHEMBL394846 | 0.76 | SHBG (0.48) | SHBGMAPTPKMNPSR1KDM4E | |
| SCHEMBL1975607 | 0.74 | GABRA1 (0.53) | GABRA1GABRB2POLBGAAMEN1 | |
| SCHEMBL17006189 | 0.74 | L3MBTL1 (0.42) | GABRA1GABRB2GAAMEN1KMT2A | |
| SCHEMBL4557644 | 0.74 | MEN1 (0.42) | GABRA1GABRB2SHBGPOLBGAA | |
| SCHEMBL9685024 | 0.73 | SHBG (0.50) | SHBGMEN1KMT2AMAPTPKM | |
| SCHEMBL9003492 | 0.72 | GABRA1 (0.49) | GABRA1GABRB2POLBGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310542-A | INSECTICIDES, ACARICIDES, NEMATOCIDES, FUNGICIDES | ROUSSEL UCLAF (FR) | 1982-01-12 | — | — | US | disclosed |
| US-4279835-A | PESTICIDES, FINGICIDES | ROUSSEL UCLAF (FR) | 1981-07-21 | — | — | US | disclosed |
| US-4231932-A | PESTICIDES | ROUSSEL UCLAF (FR) | 1980-11-04 | — | — | US | disclosed |
| US-4224227-A | PESTICIDES | ROUSSEL UCLAF (FR) | 1980-09-23 | — | — | US | disclosed |