Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10410053 | 0.75 | CES2 (0.41) | — | |
| SCHEMBL8608901 | 0.75 | TSHR (0.52) | HTR1ADRD2HTR2AHTR7NPC1 | |
| SCHEMBL15961517 | 0.75 | ALDH1A1 (0.45) | HTR1ADRD2HTR2AHTR7NPC1 | |
| SCHEMBL11428312 | 0.73 | ALDH1A1 (0.50) | — | |
| SCHEMBL10028024 | 0.73 | HTR1A (0.37) | HTR1ADRD2HTR2AHTR7NPC1 | |
| SCHEMBL11338601 | 0.73 | HTR1A (0.37) | HTR1ADRD2HTR2AHTR7NPC1 | |
| SCHEMBL13701324 | 0.71 | TDP1 (0.41) | HTR1ADRD2HTR2AHTR7NPC1 | |
| SCHEMBL9883725 | 0.71 | SMN1; SMN2 (0.36) | HTR1ADRD2HTR2AHTR7NPC1 | |
| SCHEMBL13814115 | 0.70 | KDM4E (0.44) | SMN1; SMN2 | |
| SCHEMBL16938128 | 0.70 | SMN1; SMN2 (0.35) | HTR1ADRD2HTR2AHTR7NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323517-A | ANTIPHLOGISTIC AGENTS | TROPONWERKE GMBH & CO. KG (DE) | 1982-04-06 | — | — | US | disclosed |
| US-4246278-A | ANTIINFLAMMATORY SULFUR-CONTAINING ORGANIC ACIDS OR ESTERS OR THIOATES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-20 | — | — | US | disclosed |