Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7349464 | 0.85 | TSHR (0.52) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL21600666 | 0.84 | TSHR (0.52) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL9883732 | 0.83 | LMNA (0.50) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL11965177 | 0.81 | TSHR (0.52) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL11965788 | 0.81 | TSHR (0.52) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL8159273 | 0.81 | TSHR (0.52) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL14720593 | 0.80 | TSHR (0.48) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL15961517 | 0.79 | ALDH1A1 (0.45) | LMNATDP1NPC1RAB9AHTR1A | |
| SCHEMBL11496709 | 0.78 | TSHR (0.46) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL2223767 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12024549-B2 | Compound having affinity substance to soluble protein, cleavable portion and reactive group, or salt thereof | AJINOMOTO CO., INC. (JP) | 2024-07-02 | — | — | US | disclosed |
| CN-116529302-A | Rubber composition, sulfide of the rubber composition, and vulcanized molded article of the rubber composition | 电化株式会社 | 2023-08-01 | — | — | CN | disclosed |
| US-20200190165-A1 | COMPOUND HAVING AFFINITY SUBSTANCE TO SOLUBLE PROTEIN, CLEAVABLE PORTION AND REACTIVE GROUP, OR SALT THEREOF | AJINOMOTO CO., INC. (JP) | 2020-06-18 | — | — | US | disclosed |
| EP-3617235-A1 | COMPOUND HAVING SUBSTANCE THAT HAS AFFINITY FOR SOLUBLE PROTEIN, CLEAVABLE MOIETY, AND REACTIVE GROUP, OR SALT THEREOF | Ajinomoto Co., Inc. (JP) | 2020-03-04 | — | — | EP | disclosed |
| EP-2480247-B1 | NOVEL NPR-B AGONISTS | SHIRE ORPHAN THERAPIES GMBH (DE) | 2020-02-12 | — | — | EP | disclosed |
| US-9099657-B2 | Photoelectric conversion element and solar cell | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2015-08-04 | — | — | US | disclosed |
| US-8668846-B2 | Photoelectric conversion element and solar cell | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2014-03-11 | — | — | US | disclosed |
| US-8471143-B2 | Photoelectric conversion element and solar cell | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2013-06-25 | — | — | US | disclosed |
| US-8410356-B2 | Photoelectric conversion element and solar cell | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2013-04-02 | — | — | US | disclosed |
| US-8410356-B2 | Photoelectric conversion element and solar cell | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2013-04-02 | — | — | US | disclosed |
| US-20100029637-A1 | Chymase Inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-04 | — | — | US | disclosed |
| US-7291443-B2 | Polymerizable composition and image-recording material using the same | FUJIFILM CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-7291443-B2 | Polymerizable composition and image-recording material using the same | FUJIFILM CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-5770701-A | Process for preparing targeted forms of methyltrithio antitumor agents | AMERICAN CYANAMID COMPANY (US) | 1998-06-23 | — | — | US | disclosed |
| US-5770710-A | REACTING METHYLTRITHIO ANTIBIOTIC LL-E32288 DERIVATIVE WITH MERCAPTAN COMPOUND | AMERICAN CYANAMID COMPANY (US) | 1998-06-23 | — | — | US | disclosed |
| US-5606040-A | DERIVATIZED OLIGOSACCHARIDE ANTIBIOTICS WITH CHROMOPHORE | AMERICAN CYANAMID COMPANY (US) | 1997-02-25 | — | — | US | disclosed |
| EP-0313873-B1 | Targeted forms of methyltrithio antitumor agents | AMERICAN CYANAMID CO (US) | 1994-09-28 | — | — | EP | disclosed |
| US-5053394-A | Protein-drug reaction product | AMERICAN CYANAMID COMPANY (US) | 1991-10-01 | — | — | US | disclosed |
| EP-0392384-A2 | Targeted forms of methyltrithio antitumor agents | AMERICAN CYANAMID COMPANY (US) | 1990-10-17 | — | — | EP | disclosed |
| EP-0313873-A1 | Targeted forms of methyltrithio antitumor agents | AMERICAN CYANAMID COMPANY (US) | 1989-05-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029637-A1 | Chymase Inhibitors | CMA1, CPA3, SERPINB1 | TSHR 3397/4885LMNA 1979/4885KMT2A 3638/4885 |
| US-20200190165-A1 | COMPOUND HAVING AFFINITY SUBSTANCE TO SOLUBLE PROTEIN, CLEAVABLE PORTION AND REACTIVE GROUP, OR SALT THEREOF | SPPL2B, CSTB, SPPL2A | TSHR 1360/4885LMNA 1617/4885KMT2A 2873/4885 |
| US-12024549-B2 | Compound having affinity substance to soluble protein, cleavable portion and reactive group, or salt thereof | SPPL2B, CSTB, SPPL2A | TSHR 1360/4885LMNA 1617/4885KMT2A 2873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.