SCHEMBL11246664

C[C@@H](CO[Si](C)(C)C(C)(C)C)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C=C(O[Si](C)(C)C)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.48

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	SRD5A2	P31213	6/20	0.48

▸	SRD5A1	P18405	4/20	0.36

▸	GPBAR1	Q8TDU6	1/20	0.35

▸	NPC1L1	Q9UHC9	1/20	0.35

▸	OSBP	P22059	1/20	0.35

▸	OSBP2	Q969R2	1/20	0.35

▸	VDR	P11473	2/20	0.33

▸	GRIN1	Q05586	1/20	0.33

▸	GRIN2A	Q12879	1/20	0.33

▸	GRIN2B	Q13224	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11246663	0.85	SRD5A2 (0.47)	SRD5A2SRD5A1GPBAR1NPC1L1OSBP
SCHEMBL9348037	0.83	SRD5A2 (0.51)	SRD5A2SRD5A1GPBAR1NPC1L1OSBP
SCHEMBL9348309	0.83	SRD5A2 (0.51)	SRD5A2SRD5A1GPBAR1NPC1L1OSBP
SCHEMBL9782796	0.82	SRD5A2 (0.59)	SRD5A2SRD5A1GPBAR1NPC1L1VDR
SCHEMBL9822553	0.82	SRD5A2 (0.59)	SRD5A2SRD5A1GPBAR1NPC1L1VDR
SCHEMBL9782666	0.74	OSBP (0.36)	SRD5A2NPC1L1OSBPOSBP2VDR
SCHEMBL9782671	0.74	OSBP (0.36)	SRD5A2NPC1L1OSBPOSBP2VDR
SCHEMBL9782729	0.74	GPBAR1 (0.39)	GPBAR1OSBPOSBP2VDRGRIN1
SCHEMBL9348135	0.74	SRD5A2 (0.41)	SRD5A2SRD5A1GPBAR1NPC1L1OSBP
SCHEMBL9348131	0.74	SRD5A2 (0.41)	SRD5A2SRD5A1GPBAR1NPC1L1OSBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-4317817-A	SKIN DISORDERS; ACEME; ENZYME INHIBITORS	RICHARDSON-MERRELL INC. (US)	1982-03-02	—	—	US	disclosed