Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28131897 | 0.96 | CYP1A2 (0.55) | CYP1A2LMNAMAPTSMN1; SMN2PTGS2 | |
| SCHEMBL7061128 | 0.95 | PTGS2 (0.57) | CYP1A2LMNAMAPTSMN1; SMN2PTGS2 | |
| SCHEMBL16024600 | 0.93 | HTR2A (0.56) | CYP1A2LMNAMAPTSMN1; SMN2PTGS2 | |
| SCHEMBL19506648 | 0.93 | HTR2A (0.56) | CYP1A2LMNAMAPTSMN1; SMN2PTGS2 | |
| SCHEMBL14783441 | 0.93 | HTR2A (0.56) | CYP1A2LMNAMAPTSMN1; SMN2PTGS2 | |
| SCHEMBL16024605 | 0.90 | HTR2A (0.53) | CYP1A2LMNAMAPTSMN1; SMN2PTGS2 | |
| SCHEMBL28841007 | 0.90 | HTR2A (0.53) | CYP1A2LMNAMAPTSMN1; SMN2PTGS2 | |
| SCHEMBL16024669 | 0.90 | HTR2A (0.53) | CYP1A2LMNAMAPTSMN1; SMN2PTGS2 | |
| SCHEMBL3162663 | 0.89 | CYP1A2 (0.62) | CYP1A2LMNAMAPTSMN1; SMN2PTGS2 | |
| SCHEMBL3153171 | 0.86 | CASP3 (0.51) | CYP1A2LMNAMAPTSMN1; SMN2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003643-B1 | PROCESS FOR THE PREPARATION OF 4-(6-METHOXY-2-NAPHTHYL)-BUTAN-2-ONE; 4-(6-METHOXY-2-NAPHTHYL)-4-HYDROXYBUT-3-EN-2-ONE AND A PROCESS FOR ITS PREPARATION | BEECHAM GROUP PLC (GB) | 1982-09-29 | — | — | EP | claimed |
| US-20230271988-A1 | METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2023-08-31 | — | — | US | disclosed |
| US-20230271988-A1 | METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2023-08-31 | — | — | US | disclosed |
| EP-2316469-A1 | Delivery system and methods for protecting and administering dextroamphetamine | Shire LLC (US) | 2011-05-04 | — | — | EP | disclosed |
| EP-2316468-A1 | Delivery system and methods for protecting and administering dextroamphetamine | Shire LLC (US) | 2011-05-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271988-A1 | METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE | HPD, TALDO1, OGG1 | CYP1A2 537/4885LMNA 4769/4885MAPT 4173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.