Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PPIB | P23284 | 1/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | PPIG | Q13427 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27458906 | 0.87 | BLM (0.51) | TSHRBLMESR1ESR2 | |
| SCHEMBL9658100 | 0.85 | BLM (0.44) | CYP3A4TSHRFDPSALDH1A1TDP1 | |
| SCHEMBL27946673 | 0.85 | HIF1A (0.50) | CYP3A4FDPSALDH1A1LMNACYP1A2 | |
| SCHEMBL27368383 | 0.82 | ALDH1A1 (0.39) | CYP3A4TSHRALDH1A1TDP1LMNA | |
| SCHEMBL28092110 | 0.81 | KDM4E (0.45) | TDP1LOXL2 | |
| SCHEMBL8272703 | 0.81 | CA2 (0.53) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8421707 | 0.79 | PRSS1 (0.40) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL23586208 | 0.78 | FDPS (0.47) | CYP3A4TSHRFDPSALDH1A1TDP1 | |
| SCHEMBL15660797 | 0.76 | FDPS (0.46) | CYP3A4TSHRFDPSALDH1A1TDP1 | |
| SCHEMBL27458539 | 0.75 | MAPT (0.44) | ALDH1A1GAAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310429-A | HEAT AND OXIDATION RESISTANT AMINOACETAMIDES | THE B. F. GOODRICH COMPANY (US) | 1982-01-12 | — | — | US | disclosed |
| EP-0007182-A1 | Stabilized polymers, novel stabilizers and synthesis thereof | The B.F. GOODRICH Company (US) | 1980-01-23 | — | — | EP | disclosed |