Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.49 |
| ▸ | HTR2B | P41595 | 5/20 | 0.49 |
| ▸ | HTR2A | P28223 | 5/20 | 0.49 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256538 | 0.86 | HTR2C (0.47) | HTR2CHTR2BHTR2ASIGMAR1BCHE | |
| SCHEMBL11258249 | 0.82 | CYP2D6 (0.49) | HTR2CHTR2BHTR2AKDM1ASIGMAR1 | |
| SCHEMBL12537100 | 0.78 | KDM1A (0.47) | HTR2CHTR2BHTR2AKDM1ABCHE | |
| SCHEMBL38663158 | 0.78 | KDM1A (0.47) | HTR2CHTR2BHTR2AKDM1ABCHE | |
| SCHEMBL9280480 | 0.77 | HTR2C (0.56) | HTR2CHTR2BHTR2APARP1 | |
| SCHEMBL11247722 | 0.75 | HTR2C (0.50) | HTR2CHTR2BHTR2APARP1 | |
| SCHEMBL11242393 | 0.73 | HTR2C (0.49) | HTR2CHTR2BHTR2APARP1MAOA | |
| SCHEMBL15006825 | 0.72 | HTR2C (0.48) | HTR2CHTR2BHTR2APARP1 | |
| SCHEMBL2709111 | 0.70 | HTR2C (0.77) | HTR2CHTR2BHTR2A | |
| SCHEMBL11241659 | 0.70 | CYP1A2 (0.42) | HTR2CHTR2BHTR2AKDM1ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360525-A | NEUROLEPTIC AGENTS, ANTIDEPRESSANTS, SLEEP PROMOTERS | SANDOZ LTD. (CH) | 1982-11-23 | — | — | US | claimed |
| US-4360525-A | NEUROLEPTIC AGENTS, ANTIDEPRESSANTS, SLEEP PROMOTERS | SANDOZ LTD. (CH) | 1982-11-23 | — | — | US | disclosed |