Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL655407 | 0.90 | KMT2A (0.62) | KMT2AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL27631447 | 0.84 | KMT2A (0.56) | KMT2AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL7432296 | 0.83 | KMT2A (0.52) | KMT2AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL1784315 | 0.79 | ALDH1A1 (0.63) | KMT2AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL6696570 | 0.77 | CHRNB2 (0.54) | KMT2AALDH1A1MEN1CHRNB2CHRNA4 | |
| Dinitrophenylene SCHEMBL27769163 | 0.77 | GLO1 (0.54) | KMT2AALDH1A1MEN1NPC1GLO1 | |
| SCHEMBL8105025 | 0.77 | KMT2A (0.53) | KMT2AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL10753064 | 0.76 | CHRNB2 (0.58) | KMT2AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL7430588 | 0.76 | NPC1 (0.52) | KMT2AALDH1A1MEN1NPC1CHRNB2 | |
| SCHEMBL31037156 | 0.76 | CHRNB2 (0.65) | KMT2AALDH1A1MEN1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310527-A | DISORDERS OF CAROIAC RHYTHM AND CORONARY HEART DISEASES AND HYDPERTENSION | CIBA-GEIGY CORPORATION (US) | 1982-01-12 | — | — | US | disclosed |
| US-4140789-A | ADRENERGIC BLOCKING AGENTS, CARDIOTONIC, ANTIARRHYTHMIA, HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1979-02-20 | — | — | US | disclosed |