Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1099049 | 0.83 | CHRNB2 (0.56) | KMT2AMAPTCTDSP1MEN1ALDH1A1 | |
| SCHEMBL29639143 | 0.83 | CHRNB2 (0.56) | KMT2AMAPTCTDSP1MEN1ALDH1A1 | |
| SCHEMBL655407 | 0.83 | KMT2A (0.62) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL14537261 | 0.81 | KMT2A (0.54) | KMT2AMAPTCTDSP1MEN1ALDH1A1 | |
| SCHEMBL8112886 | 0.80 | RAB9A (0.48) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL1784315 | 0.80 | ALDH1A1 (0.63) | KMT2AMAPTCTDSP1MEN1ALDH1A1 | |
| SCHEMBL14481735 | 0.79 | HTT (0.49) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL8116474 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL7670870 | 0.79 | CHRNB2 (0.51) | KMT2AMAPTCTDSP1MEN1ALDH1A1 | |
| SCHEMBL217722 | 0.78 | LMNA (0.57) | KMT2AMAPTCTDSP1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590885-B1 | Antibiotic carbapenem compounds | ZENECA LTD (GB) | 2000-03-15 | — | — | EP | disclosed |
| US-5527791-A | Carbapenem antibiotic compounds | ZENECA LIMITED (GB) | 1996-06-18 | — | — | US | disclosed |
| EP-0590885-A1 | Antibiotic carbapenem compounds | ZENECA LIMITED (GB) | 1994-04-06 | — | — | EP | disclosed |