Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14644904 | 0.80 | EPHX2 (0.57) | EPHX2ALDH1A1SMN1; SMN2LMNATHRB | |
| Acrylic Acid SCHEMBL31456574 | 0.78 | LMNA (0.49) | EPHX2ALDH1A1SMN1; SMN2LMNATHRB | |
| SCHEMBL8213486 | 0.77 | EPHX2 (0.53) | EPHX2ALDH1A1SMN1; SMN2LMNATHRB | |
| SCHEMBL13320026 | 0.77 | LMNA (0.58) | EPHX2ALDH1A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL28690139 | 0.77 | ALDH1A1 (0.50) | EPHX2ALDH1A1SMN1; SMN2LMNATHRB | |
| SCHEMBL13320029 | 0.76 | L3MBTL1 (0.58) | EPHX2ALDH1A1SMN1; SMN2LMNATHRB | |
| SCHEMBL17348282 | 0.75 | L3MBTL1 (0.54) | EPHX2ALDH1A1SMN1; SMN2LMNATHRB | |
| SCHEMBL13320019 | 0.75 | L3MBTL1 (0.57) | EPHX2ALDH1A1SMN1; SMN2LMNATHRB | |
| SCHEMBL1065700 | 0.74 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL7797331 | 0.74 | ALDH1A1 (0.50) | EPHX2ALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013663-B1 | PROCESS FOR REMOVING AN ALLYLIC GROUP FROM ALLYLIC ESTERS, CARBONATES AND CARBAMATES | SCHERING CORPORATION (US) | 1982-11-17 | — | — | EP | disclosed |
| US-4314942-A | Deprotection of allylic esters, carbonates and carbamates catalyzed by palladium compounds | SCHERING CORPORATION (US) | 1982-02-09 | — | — | US | disclosed |
| EP-0013663-A1 | Process for removing an allylic group from allylic esters, carbonates and carbamates | SCHERING CORPORATION (US) | 1980-07-23 | — | — | EP | disclosed |