Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241887 | 0.93 | KDM4E (0.40) | KDM4EALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL3453702 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL11570772 | 0.78 | KDM4E (0.56) | KDM4EALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL11574238 | 0.77 | KDM4E (0.56) | KDM4EALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL11252736 | 0.72 | KDM4E (0.46) | KDM4EALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL11570132 | 0.71 | KDM4E (0.57) | KDM4EALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL11241401 | 0.69 | ADRA1D (0.43) | KDM4EALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL8810668 | 0.69 | LMNA (0.56) | ALDH1A1HPGDGAATP53TSHR | |
| SCHEMBL13483289 | 0.68 | ALDH1A1 (0.69) | KDM4EALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL11253598 | 0.67 | KDM4E (0.42) | KDM4EALDH1A1HPGDGLAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004389-B1 | 4-AMINO-6,7-DIMETHOXY QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AND A PHARMACEUTICAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-04-07 | — | — | EP | claimed |
| EP-0088932-A1 | Heat resistant hot melt adhesives | National Starch and Chemical Corporation (US) | 1983-09-21 | — | — | EP | disclosed |
| EP-0004389-B1 | 4-AMINO-6,7-DIMETHOXY QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AND A PHARMACEUTICAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-04-07 | — | — | EP | disclosed |