SCHEMBL11248210

SCHEMBL11248210

C=CCC(C#CC)(NC(C)=O)C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3402649 0.71 PKM (0.36) ALDH1A1TSHR
SCHEMBL3485811 0.69 NAALAD2 (0.41) ALDH1A1TSHR
SCHEMBL11248213 0.69 POLB (0.33)
SCHEMBL992620 0.66 PKM (0.32)
SCHEMBL25446073 0.65 KDM4E (0.31)
SCHEMBL8500067 0.63 KDM4E (0.36)
SCHEMBL17039269 0.63 EPHX1 (0.34)
SCHEMBL8585464 0.61 MAPT (0.38) ALDH1A1TSHR
SCHEMBL11000050 0.60 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL10544728 0.60 ALDH1A1 (0.39) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4323704-A ENZYME INHIBITORS USEFUL AGAINST BACTERIA, FUNGUS AND VIRAL INFECTIONS, MALE ANTIFERTILITY AGENTS, IMMUNO-SUPPRESSANTS, AND ANTITUMOR ACTIVITY MERRELL TORAUDE ET COMPAGNIE (FR) 1982-04-06 US disclosed
US-4267374-A BACTERICIDES; VIRICIDES; FUNGICIDES; INHIBITORS OF HYDROLASE ENZYMES; INTERMEDIATE FOR CEPHALOSPORIN COMPOUND MERRELL TORAUDE ET COMPAGNIE (FR) 1981-05-12 US disclosed