Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 6/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | TNKS | O95271 | 4/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.38 |
| ▸ | WNT3A | P56704 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262196 | 0.84 | NPBWR1 (0.41) | TRPV1NPBWR1DGAT1KCNH2TNKS | |
| SCHEMBL11243176 | 0.83 | TRPV1 (0.47) | TRPV1DGAT1TNKSTNKS2PARP1 | |
| SCHEMBL11249122 | 0.79 | NPBWR1 (0.31) | NPBWR1 | |
| SCHEMBL11258445 | 0.78 | ABCC8 (0.36) | NPBWR1 | |
| SCHEMBL11261336 | 0.78 | MPL (0.36) | NPBWR1 | |
| SCHEMBL11247198 | 0.77 | TRPV1 (0.36) | TRPV1NPBWR1DGAT1KCNH2TNKS | |
| SCHEMBL11267114 | 0.76 | TRPV1 (0.45) | TRPV1KCNH2TNKS2WNT3A | |
| SCHEMBL10553745 | 0.76 | KDM4E (0.48) | TNKSTNKS2GFERPARP1MAPK13 | |
| SCHEMBL11258492 | 0.75 | — | — | |
| SCHEMBL11246854 | 0.75 | PPARG (0.38) | TRPV1NPBWR1DGAT1KCNH2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |