Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250776 | 0.90 | ABCC8 (0.44) | ABCC8KCNJ11PTGESHDAC3HDAC7 | |
| SCHEMBL11249122 | 0.87 | NPBWR1 (0.31) | NPBWR1 | |
| SCHEMBL11261336 | 0.86 | MPL (0.36) | NPBWR1 | |
| SCHEMBL11246933 | 0.82 | PTGES (0.43) | ABCC8KCNJ11PTGESHDAC3HDAC7 | |
| SCHEMBL11248485 | 0.78 | TRPV1 (0.40) | NPBWR1 | |
| SCHEMBL11262992 | 0.78 | AKR1C3 (0.33) | PTGESHDAC3HDAC7HDAC10HDAC6 | |
| SCHEMBL11261371 | 0.77 | GPR3 (0.39) | PTGESPOLBGAA | |
| SCHEMBL11241077 | 0.75 | MPL (0.44) | ABCC8KCNJ11NPBWR1 | |
| SCHEMBL11245992 | 0.75 | HDAC3 (0.41) | PTGESHDAC3HDAC7HDAC10HDAC6 | |
| SCHEMBL11253894 | 0.75 | ALDH1A1 (0.37) | ABCC8KCNJ11PTGESHDAC3HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |