SCHEMBL1124850

SCHEMBL1124850

O=Cc1ccc(C(=O)O)c(O)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 5/20 0.65
KDM4E B2RXH2 6/20 0.59
PTGS2 P35354 1/20 0.59
RAB9A P51151 1/20 0.59
ALDH1A1 P00352 8/20 0.57
CA12 O43570 2/20 0.57
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
CA7 P43166 2/20 0.57
CA9 Q16790 2/20 0.57
CA14 Q9ULX7 2/20 0.57
TSHR P16473 1/20 0.57
MAPT P10636 2/20 0.53
CYP3A4 P08684 1/20 0.53
GAA P10253 1/20 0.53
ESR2 Q92731 1/20 0.53
HNF4A P41235 2/20 0.50
PTPN2 P17706 1/20 0.50
PTPN6 P29350 1/20 0.50
ACMSD Q8TDX5 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2561873 0.85 ACMSD (0.68) PTPN1KDM4EPTGS2ALDH1A1CA12
SCHEMBL29354644 0.83 PTPN1 (0.71) PTPN1KDM4EPTGS2RAB9AALDH1A1
SCHEMBL130917 0.83 PTPN1 (0.71) PTPN1KDM4EPTGS2RAB9AALDH1A1
SCHEMBL4613992 0.83 ALDH1A1 (0.52) PTPN1KDM4EPTGS2RAB9AALDH1A1
SCHEMBL30589393 0.83 ALDH1A1 (0.52) PTPN1KDM4EPTGS2RAB9AALDH1A1
SCHEMBL16232846 0.82 KDM4E (0.57) PTPN1KDM4EPTGS2RAB9AALDH1A1
SCHEMBL1813719 0.82 PTPN1 (0.62) PTPN1KDM4EPTGS2ALDH1A1CA12
Hydrochloric Acid SCHEMBL26602132 0.82 PTPN1 (0.69) PTPN1KDM4EPTGS2RAB9AALDH1A1
SCHEMBL29957499 0.82 KDM4E (0.57) PTPN1KDM4EPTGS2RAB9AALDH1A1
SCHEMBL2560683 0.81 ACMSD (0.67) PTPN1ALDH1A1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122005693-A Application of Jiaweidanzhi Xiaoyao powder or extract thereof in preparation of medicines for treating depression complicated with ulcerative colitis 河南中医药大学 2026-05-12 CN claimed
CN-117819654-B Process method for removing algae in drinking water source 北京太和洁源科技发展有限公司 2024-06-28 CN claimed
CN-117819654-A Process method for removing algae in drinking water source 北京太和洁源科技发展有限公司 2024-04-05 CN claimed
US-20130210913-A1 ANTI-TUMOR AND ANTI-INFLAMMATORY DICINNAMOYL-GLYCEROL ESTERS AND THEIR ANALOGUES UNIVERSITY OF MARYLAND, BALTIMORE 2013-08-15 US claimed
JP-4587669-B2 2010-11-24 JP claimed
JP-2005509662-A 2005-04-14 JP claimed
CN-1589136-A Pharmaceutical and cosmetic compositions containing aromatic aldehydes bearing oxygen-containing groups CUTANIX CORP (US) 2005-03-02 CN claimed
EP-1443915-A1 PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES Cutanix Corporation (US) 2004-08-11 EP claimed
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments CUTANIX CORPORATION 2003-08-21 US claimed
WO-2003043621-A1 PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES CUTANIX CORPORATION (US) 2003-05-30 WO claimed
CN-122005693-A Application of Jiaweidanzhi Xiaoyao powder or extract thereof in preparation of medicines for treating depression complicated with ulcerative colitis 河南中医药大学 2026-05-12 CN disclosed
US-20250114466-A1 ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES BYONDIS B.V. (NL) 2025-04-10 US disclosed
EP-4457229-A1 ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES Byondis B.V. (NL) 2024-11-06 EP disclosed
CN-118613484-A Antifolate linker-drug and antibody-drug conjugates 拜奥迪斯私人有限公司 2024-09-06 CN disclosed
CN-117819654-B Process method for removing algae in drinking water source 北京太和洁源科技发展有限公司 2024-06-28 CN disclosed
EP-0552282-B1 BI-AROMATIC COMPOUNDS AND THEIR USE IN HUMAN AND VETERINARY MEDECINE AND IN COSMETIC PREPARATIONS CIRD GALDERMA (FR) 1994-08-24 EP disclosed
EP-0552282-A1 BI-AROMATIC COMPOUNDS AND THEIR USE IN HUMAN AND VETERINARY MEDECINE AND IN COSMETIC PREPARATIONS. CIRD GALDERMA (FR) 1993-07-28 EP disclosed
WO-1992020643-A1 NOVEL BI-AROMATIC COMPOUNDS DERIVED FROM A SALICILIC PATTERN, METHOD OF PREPARATION AND USE IN HUMAN AND VETERINARY MEDECINE AND IN COSMETICS CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) 1992-11-26 WO disclosed
EP-0514264-A1 Biaromatic compounds derived from compounds having a salicylic configuration, their preparation process and their use in human and veterinary medicine and in cosmetics CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) 1992-11-19 EP disclosed
WO-1992006948-A1 BI-AROMATIC COMPOUNDS AND THEIR USE IN HUMAN AND VETERINARY MEDECINE AND IN COSMETIC PREPARATIONS CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) 1992-04-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250114466-A1 ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES DHFR, FOLR1, MTHFD2 PTPN1 3920/4885KDM4E 2050/4885PTGS2 2219/4885
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments TYR, HRH1, HRH2 PTPN1 2853/4885KDM4E 2158/4885PTGS2 484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.