Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245302 | 0.93 | L3MBTL1 (0.55) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7591829 | 0.91 | PDK1 (0.58) | NPC1RAB9ASMN1; SMN2MAPTPDK1 | |
| SCHEMBL14290702 | 0.79 | POLB (0.44) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL19707372 | 0.78 | MAPT (0.47) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11249289 | 0.77 | PDK1 (0.60) | NPC1RAB9ASMN1; SMN2MAPTPDK1 | |
| SCHEMBL3820709 | 0.76 | MAPT (0.49) | NPC1RAB9ASMN1; SMN2MAPTPDK1 | |
| SCHEMBL366747 | 0.76 | SMN1; SMN2 (0.74) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4110532 | 0.76 | L3MBTL1 (0.83) | NPC1RAB9AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL17227570 | 0.75 | AR (0.49) | SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL18086475 | 0.74 | L3MBTL1 (0.59) | NPC1RAB9ASMN1; SMN2MAPTPDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310429-A | HEAT AND OXIDATION RESISTANT AMINOACETAMIDES | THE B. F. GOODRICH COMPANY (US) | 1982-01-12 | — | — | US | disclosed |
| EP-0007182-A1 | Stabilized polymers, novel stabilizers and synthesis thereof | The B.F. GOODRICH Company (US) | 1980-01-23 | — | — | EP | disclosed |