SCHEMBL4110532

SCHEMBL4110532

Cc1ccc(NC(=O)C(C)(C)C)cc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.83
▸ MAPT P10636 3/20 0.63
▸ ALDH1A1 P00352 1/20 0.63
▸ CA12 O43570 1/20 0.59
▸ CA1 P00915 1/20 0.59
▸ CA2 P00918 1/20 0.59
▸ CA7 P43166 1/20 0.59
▸ CA9 Q16790 1/20 0.59
▸ CA14 Q9ULX7 1/20 0.59
▸ TDP1 Q9NUW8 1/20 0.59
▸ POLB P06746 1/20 0.57
▸ LMNA P02545 2/20 0.56
▸ NPC1 O15118 2/20 0.55
▸ RAB9A P51151 2/20 0.55
▸ HDAC1 Q13547 1/20 0.54
▸ HDAC7 Q8WUI4 1/20 0.54
▸ HDAC8 Q9BY41 1/20 0.54
▸ NPSR1 Q6W5P4 1/20 0.53
▸ KIF11 P52732 1/20 0.52
▸ TGM2 P21980 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7733701 0.91 L3MBTL1 (1.00) L3MBTL1MAPTALDH1A1CA12CA1
SCHEMBL18086475 0.85 L3MBTL1 (0.59) L3MBTL1MAPTTDP1POLBNPC1
SCHEMBL17368411 0.83 KIF11 (0.58) L3MBTL1MAPTCA12CA1CA2
SCHEMBL1176666 0.83 L3MBTL1 (0.83) L3MBTL1MAPTALDH1A1CA12CA1
SCHEMBL18033762 0.83 L3MBTL1 (0.83) L3MBTL1MAPTALDH1A1CA12CA1
SCHEMBL8777217 0.83 L3MBTL1 (0.83) L3MBTL1MAPTALDH1A1CA12CA1
SCHEMBL1422823 0.83 L3MBTL1 (0.83) L3MBTL1MAPTALDH1A1CA12CA1
SCHEMBL1176999 0.82 L3MBTL1 (0.73) L3MBTL1MAPTALDH1A1CA12CA1
SCHEMBL11245302 0.82 L3MBTL1 (0.55) L3MBTL1MAPTALDH1A1TDP1POLB
SCHEMBL15270323 0.81 L3MBTL1 (0.79) L3MBTL1MAPTALDH1A1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119954705-A Indole derivative and preparation method thereof 南阳师范学院 2025-05-09 — — CN claimed
US-20260056161-A1 THIN LAYER TYPE ELECTROCHEMICAL SYSTEM INCLUDING SALT BRIDGE AND ELECTROCHEMICAL ANALYSIS METHOD USING THE SAME SEOUL NAT UNIV R&DB FOUNDATION (KR) 2026-02-26 — — US disclosed
CN-119954705-A Indole derivative and preparation method thereof 南阳师范学院 2025-05-09 — — CN disclosed
CN-113912529-B Method for synthesizing indole compounds by catalyzing N-aryl amide compounds and vinylene carbonate with ruthenium 成都大学 2023-07-25 — — CN disclosed
WO-2023109912-A1 3, 4-DIHYDROISOQUINOLIN-1 (2H) -ONES DERIVATIVES AS STING ANTAGONISTS AND THE USE THEREOF BEIGENE, LTD. (KY) 2023-06-22 — — WO disclosed
US-11680074-B2 Compounds, functionalised dioxaborolane or dioxaborinane derivatives, method for preparing same and uses thereof ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (FR) 2023-06-20 — — US disclosed
WO-2023033271-A1 THIN FILM-TYPE ELECTROCHEMICAL SYSTEM COMPRISING SALT BRIDGE AND ELECTROCHEMICAL ANALYSIS METHOD USING SAME 서울대학교산학협력단 2023-03-09 — — WO disclosed
EP-3464300-B1 NOVEL COMPOUNDS, FUNCTIONALISED DIOXABOROLANE OR DIOXABORINANE DERIVATIVES, METHOD FOR PREPARING SAME AND USES THEREOF ECOLE SUPERIEURE DE PHYSIQUE ET CHIMIE IND DE LA VILLE DE PARIS (FR) 2021-12-01 — — EP disclosed
WO-2021130638-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS CARNA BIOSCIENCES, INC. (JP) 2021-07-01 — — WO disclosed
EP-3412660-B9 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME EA PHARMA CO LTD (JP) 2021-04-14 — — EP disclosed
US-6303780-B1 4,4-disubstituted-1,4-dihydro-2h-3,1-benzoxazin-2-ones useful as HIV reverse transcriptase inhibitors and intermediates and processes for making the same DUPONT PHARMACEUTICALS COMPANY 2001-10-16 — — US disclosed
US-6140499-A 4,4-disubstituted-1,4-dihydro-2H-3,1-benzoxazin-2-ones useful as HIV reverse transcriptase inhibitors and intermediates and processes for making the same DUPONT PHARMACEUTICAL COMPANY (US) 2000-10-31 — — US disclosed
EP-0929533-A1 4,4-DISUBSTITUTED-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONES USEFUL AS HIV REVERSE TRANSCRIPTASE INHIBITORS AND INTERMEDIATES AND PROCESSES FOR MAKING THE SAME Du Pont Pharmaceuticals Company (US) 1999-07-21 — — EP disclosed
US-5874430-A COMPOUNDS AS PROTEASE, REVERSE TRANSCRIPTASE INHIBITORS FOR DIAGNOSIS DUPONT PHARMACEUTICALS COMPANY (US) 1999-02-23 — — US disclosed
WO-1998014436-A1 4,4-DISUBSTITUTED-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONES USEFUL AS HIV REVERSE TRANSCRIPTASE INHIBITORS AND INTERMEDIATES AND PROCESSES FOR MAKING THE SAME DUPONT PHARMACEUTICALS COMPANY (US) 1998-04-09 — — WO disclosed
US-5633218-A CONTROLLING WEEDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-05-27 — — US disclosed
US-5631206-A Herbicidal heteroaryl substituted anilides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-05-20 — — US disclosed
EP-0722441-A1 HERBICIDAL HETEROARYL SUBSTITUTED ANILIDES E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) 1996-07-24 — — EP disclosed
EP-0619804-B1 HERBICIDAL ACYLATED AMINO-(PHENYL- OR PYRIDINYL- OR THIENYL-)-PHENYL DERIVATIVES DU PONT (US) 1996-05-22 — — EP disclosed
WO-1995009846-A1 HERBICIDAL HETEROARYL SUBSTITUTED ANILIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-04-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260056161-A1 THIN LAYER TYPE ELECTROCHEMICAL SYSTEM INCLUDING SALT BRIDGE AND ELECTROCHEMICAL ANALYSIS METHOD USING THE SAME SLC9A2, SLC9A3, SLC9A1 L3MBTL1 4802/4885MAPT 3154/4885ALDH1A1 2045/4885
US-11680074-B2 Compounds, functionalised dioxaborolane or dioxaborinane derivatives, method for preparing same and uses thereof RDX, XDH, NOX4 L3MBTL1 3728/4885MAPT 4464/4885ALDH1A1 944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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