Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NMT1 | P30419 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248665 | 0.93 | NPC1 (0.53) | L3MBTL1TDP1POLBRAB9ANPC1 | |
| SCHEMBL14290702 | 0.85 | POLB (0.44) | L3MBTL1TDP1POLBRAB9ANPC1 | |
| SCHEMBL11249289 | 0.83 | PDK1 (0.60) | L3MBTL1TDP1POLBRAB9ANPC1 | |
| SCHEMBL7591829 | 0.82 | PDK1 (0.58) | L3MBTL1POLBRAB9ANPC1HDAC1 | |
| SCHEMBL4110532 | 0.82 | L3MBTL1 (0.83) | L3MBTL1TDP1POLBRAB9ANPC1 | |
| SCHEMBL17227570 | 0.81 | AR (0.49) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL18086475 | 0.80 | L3MBTL1 (0.59) | L3MBTL1TDP1POLBRAB9ANPC1 | |
| SCHEMBL19707372 | 0.80 | MAPT (0.47) | TDP1POLBRAB9ANPC1KIF11 | |
| SCHEMBL14269954 | 0.78 | KIF11 (0.48) | TDP1POLBRAB9ANPC1KIF11 | |
| SCHEMBL17368411 | 0.78 | KIF11 (0.58) | L3MBTL1TDP1POLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310429-A | HEAT AND OXIDATION RESISTANT AMINOACETAMIDES | THE B. F. GOODRICH COMPANY (US) | 1982-01-12 | — | — | US | claimed |
| US-4310429-A | HEAT AND OXIDATION RESISTANT AMINOACETAMIDES | THE B. F. GOODRICH COMPANY (US) | 1982-01-12 | — | — | US | disclosed |
| EP-0007182-A1 | Stabilized polymers, novel stabilizers and synthesis thereof | The B.F. GOODRICH Company (US) | 1980-01-23 | — | — | EP | disclosed |