Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TK1 | P04183 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250134 | 0.87 | ALDH1A1 (0.59) | ALDH1A1LMNAMAPTPOLBKMT2A | |
| SCHEMBL8784500 | 0.77 | LMNA (0.69) | ALDH1A1LMNAMAPTPOLBKMT2A | |
| SCHEMBL19203480 | 0.77 | LMNA (0.69) | ALDH1A1LMNAMAPTPOLBKMT2A | |
| SCHEMBL9839754 | 0.77 | LMNA (0.69) | ALDH1A1LMNAMAPTPOLBKMT2A | |
| SCHEMBL5982403 | 0.76 | TK1 (0.64) | LMNASMN1; SMN2TK1CYP1A2 | |
| SCHEMBL5983317 | 0.76 | TK1 (0.64) | LMNASMN1; SMN2TK1CYP1A2 | |
| SCHEMBL22859903 | 0.75 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTPOLBKMT2A | |
| SCHEMBL30696580 | 0.74 | KMT2A (0.53) | ALDH1A1LMNAMAPTPOLBKMT2A | |
| SCHEMBL20897747 | 0.74 | KMT2A (0.53) | ALDH1A1LMNAMAPTPOLBKMT2A | |
| SCHEMBL22859783 | 0.73 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329460-A | ANTICANCER AGENTS, ANTIVIRAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-11 | — | — | US | disclosed |