SCHEMBL11248749

SCHEMBL11248749

Fc1cc(Cl)cc(F)c1-c1nc(Br)c(C(F)(F)F)[nH]1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PSD A5PKW4 4/20 0.32
HTT P42858 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PTGES O14684 2/20 0.32
KCNQ3 O43525 2/20 0.31
KCNQ2 O43526 2/20 0.31
S1PR4 O95977 1/20 0.31
AMY1A P0DUB6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11251809 0.92 PTGES (0.34) PSDHTTPTGESS1PR4
SCHEMBL11245386 0.92 AMY1A (0.33) PSDAMY1A
SCHEMBL11257902 0.88 DHODH (0.32)
SCHEMBL11253986 0.88 PTGES (0.30) PTGES
SCHEMBL11249401 0.87 CACNA1H (0.31)
SCHEMBL11252508 0.85 NPBWR1 (0.35) PSDHTTHSD17B10KCNQ3KCNQ2
SCHEMBL11261743 0.84 PTGES (0.36) PSDPTGES
SCHEMBL11252326 0.84 PTGES (0.34) PTGES
SCHEMBL11244118 0.83 CBFB (0.34) PTGES
SCHEMBL11251103 0.83 ALDH1A1 (0.41) PSDHTTHSD17B10KCNQ3KCNQ2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4314844-A FUNGICIDES ROHM AND HAAS COMPANY (US) 1982-02-09 US disclosed