Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29200760 | 0.82 | MAPT (0.55) | HCAR3MAPTSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL31612034 | 0.80 | HCAR3 (0.68) | HCAR3MAPTSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL11280733 | 0.78 | KMT2A (0.56) | HCAR3MAPTSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL28558455 | 0.78 | SCN1A (0.44) | HCAR3MAPTSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL28635267 | 0.77 | ALDH1A1 (0.46) | MAPTSMN1; SMN2HTTALDH1A1NPC1 | |
| SCHEMBL11249148 | 0.76 | KMT2A (0.60) | MAPTSMN1; SMN2HTTALDH1A1NPC1 | |
| SCHEMBL28718122 | 0.75 | MYC (0.49) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL27714575 | 0.72 | NT5E (0.39) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL7353109 | 0.71 | PDE5A (0.50) | HCAR3MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL17941243 | 0.70 | PTPN2 (0.68) | MAPTSMN1; SMN2HTTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316021-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1982-02-16 | — | — | US | disclosed |
| US-4243813-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4196125-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4118573-A | ANTIVIRAL AGENTS | ELI LILLY AND COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4018790-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-4008243-A | Antiviral thiazolinyl or thiazinyl benzimidazole esters | ELI LILLY AND COMPANY (US) | 1977-02-15 | — | — | US | disclosed |