Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | MC4R | P32245 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028091 | 0.80 | VCAM1 (0.60) | KMT2AVCAM1MAPTALDH1A1LMNA | |
| SCHEMBL7353109 | 0.79 | PDE5A (0.50) | KMT2AMAPTLMNANPSR1HPGD | |
| SCHEMBL13169514 | 0.77 | PTPN2 (0.68) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL20100945 | 0.77 | PTPN2 (0.68) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL17941243 | 0.77 | PTPN2 (0.68) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL10328475 | 0.77 | VCAM1 (0.70) | KMT2AVCAM1MAPTALDH1A1LMNA | |
| SCHEMBL27770136 | 0.77 | VCAM1 (0.70) | KMT2AVCAM1MAPTALDH1A1LMNA | |
| SCHEMBL30425957 | 0.77 | SLC6A3 (0.53) | KMT2AMAPTLMNANPSR1HPGD | |
| SCHEMBL51755 | 0.76 | LMNA (0.72) | KMT2AVCAM1MAPTALDH1A1LMNA | |
| SCHEMBL27400395 | 0.76 | PTPN2 (0.70) | MAPTALDH1A1LMNAHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316021-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1982-02-16 | — | — | US | disclosed |
| US-4243813-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4196125-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4118573-A | ANTIVIRAL AGENTS | ELI LILLY AND COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4018790-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-4008243-A | Antiviral thiazolinyl or thiazinyl benzimidazole esters | ELI LILLY AND COMPANY (US) | 1977-02-15 | — | — | US | disclosed |