Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2582091 | 0.84 | ALDH1A1 (0.58) | ALDH1A1LMNAEPHX1GAAALOX12 | |
| SCHEMBL2582084 | 0.84 | ALDH1A1 (0.58) | ALDH1A1LMNAEPHX1GAAALOX12 | |
| SCHEMBL8759659 | 0.78 | LMNA (0.53) | ALDH1A1LMNAGAAKDM4ESMN1; SMN2 | |
| SCHEMBL16989172 | 0.76 | TACR3 (0.49) | LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16989173 | 0.76 | TACR3 (0.49) | LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL250886 | 0.76 | TACR3 (0.49) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2734034 | 0.75 | LMNA (0.56) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11572811 | 0.75 | KMT2A (0.58) | ALDH1A1LMNAEPHX1GAAALOX12 | |
| SCHEMBL28056671 | 0.74 | EPHX1 (0.70) | ALDH1A1EPHX1GAAALOX12KDM4E | |
| SCHEMBL10338251 | 0.73 | GAA (0.50) | ALDH1A1LMNAGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315020-A | Oxazoline (trifluoroethyl) amine | SCIENCE UNION ET CIE (FR) | 1982-02-09 | — | — | US | disclosed |
| US-4315019-A | Novel aryltrifluoroethylamines and processes for producing the same | SCIENCE UNION ET CIE (FR) | 1982-02-09 | — | — | US | disclosed |
| US-4267345-A | 2-//PYRROL-2-YL, THIEN-2-YL, OR FUR-2-YL/-ALPHA-TRIFLUOROALKYL-AMINOOXAZOLINES; HYPOTENSIVE AGENTS | SCIENCE UNION ET CIE (FR) | 1981-05-12 | — | — | US | disclosed |