Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251540 | 0.95 | IGF1R (0.49) | IGF1RALOX15SIGMAR1OPRK1OPRM1 | |
| SCHEMBL11251025 | 0.85 | IGF1R (0.38) | IGF1RALOX15SIGMAR1OPRK1OPRM1 | |
| SCHEMBL11257276 | 0.85 | MAOB (0.45) | IGF1RALOX15ALOX5HTR2ATSHR | |
| SCHEMBL10335572 | 0.85 | ALOX15 (0.56) | IGF1RALOX15SIGMAR1OPRK1OPRM1 | |
| SCHEMBL8749788 | 0.81 | ESR1 (0.46) | SIGMAR1TYRALOX5ADRB2SLC6A2 | |
| SCHEMBL11256383 | 0.79 | ALOX5 (0.43) | IGF1RALOX15OPRK1OPRM1OPRD1 | |
| SCHEMBL11247971 | 0.79 | TDP1 (0.43) | TYRLMNAADRB2DRD3 | |
| SCHEMBL10532360 | 0.79 | RORC (0.45) | ALOX15KDM4ETYRALOX5LMNA | |
| SCHEMBL8861378 | 0.78 | TYR (0.45) | ALOX15KDM4ETYRALOX5LMNA | |
| SCHEMBL11158528 | 0.77 | OPRK1 (0.50) | OPRK1OPRM1OPRD1ADRA2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314693-B2 | Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| EP-0009386-B1 | 2,10-DISUBSTITUTED DIBENZO(B,D)PYRANS AND BENZO(C)QUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER INC. (US) | 1982-11-17 | — | — | EP | disclosed |
| US-4206225-A | ANALGESICS | PFIZER INC. (US) | 1980-06-03 | — | — | US | disclosed |
| EP-0009386-A1 | 2,10-Disubstituted dibenzo(b,d)pyrans and benzo(c)quinolines and pharmaceutical compositions thereof | PFIZER INC. (US) | 1980-04-02 | — | — | EP | disclosed |