Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 8/20 | 0.65 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | QPCT | Q16769 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255655 | 0.86 | TBXAS1 (0.56) | TBXAS1CYP19A1PLA2G4A | |
| SCHEMBL11261566 | 0.86 | KDM4E (0.63) | TBXAS1SMN1; SMN2LMNAPLA2G4AKDM4E | |
| SCHEMBL11240600 | 0.85 | CYP19A1 (0.60) | TBXAS1CYP19A1KDM4EGAAALDH1A1 | |
| SCHEMBL11260419 | 0.84 | TBXAS1 (0.59) | TBXAS1 | |
| SCHEMBL11259784 | 0.83 | TBXAS1 (0.55) | TBXAS1SMN1; SMN2KDM4EALDH1A1QPCT | |
| SCHEMBL11178893 | 0.81 | PLA2G4A (0.72) | TBXAS1CYP19A1SMN1; SMN2LMNAPLA2G4A | |
| SCHEMBL11236348 | 0.81 | CYP19A1 (0.56) | TBXAS1CYP19A1ALDH1A1QPCT | |
| SCHEMBL11238134 | 0.81 | MEN1 (0.59) | TBXAS1CYP19A1KDM4EGAAALDH1A1 | |
| SCHEMBL11265550 | 0.81 | TBXAS1 (0.57) | TBXAS1CYP19A1PLA2G4A | |
| SCHEMBL11242023 | 0.79 | KMT2A (0.53) | TBXAS1SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |