Triaziquone

Triaziquone

SCHEMBL112498

CC(S)C(=O)O.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.39
MAPT P10636 2/20 0.37
TP53 P04637 1/20 0.37
STAT3 P40763 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
APAF1 O14727 2/20 0.33
TDP2 O95551 2/20 0.33
NSD2 O96028 2/20 0.33
HKDC1 Q2TB90 2/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
GALK1 P51570 1/20 0.32
BLM P54132 1/20 0.32
ATM Q13315 1/20 0.32
NOD2 Q9HC29 1/20 0.32
ATG4B Q9Y4P1 1/20 0.32
DHODH Q02127 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL11583629 0.90 DNMT1 (0.41) DNMT1MAPTTP53STAT3HTT
Triaziquone SCHEMBL6535620 0.89 DNMT1 (0.40) DNMT1MAPTTP53STAT3HTT
Triaziquone SCHEMBL11545270 0.89 DNMT1 (0.42) DNMT1MAPTTP53STAT3HTT
Triaziquone SCHEMBL4082601 0.88 DNMT1 (0.39) DNMT1MAPTTP53STAT3HTT
Triaziquone SCHEMBL6243103 0.85 DNMT1 (0.36) DNMT1MAPTTP53STAT3HTT
Triaziquone SCHEMBL6258049 0.85 DNMT1 (0.36) DNMT1MAPTTP53STAT3HTT
Triaziquone SCHEMBL16419 0.85 MAPT (0.42) DNMT1MAPTTP53STAT3HTT
Triaziquone SCHEMBL11422311 0.85 MAPT (0.42) DNMT1MAPTTP53STAT3HTT
Triaziquone SCHEMBL4608905 0.85 DNMT1 (0.43) DNMT1MAPTTP53STAT3HTT
Triaziquone SCHEMBL10414999 0.83 MAPT (0.41) DNMT1MAPTTP53STAT3HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118317991-A Isocyanate composition and optical composition 韩华思路信(株) 2024-07-09 CN claimed
CN-115443296-B Diisocyanate composition and optical lens produced using the same 爱思开核心聚氨酯有限公司 2024-05-07 CN claimed
CN-115443296-A Diisocyanate composition and optical lens produced using the same SKC株式会社 2022-12-06 CN claimed
WO-2021215606-A1 DIISOCYANATE COMPOSITION AND OPTICAL LENS PRODUCED USING SAME 에스케이씨 주식회사 (KR) 2021-10-28 WO claimed
EP-2111877-B1 Bioabsorbable surgical composition COVIDIEN LP (US) 2013-09-18 EP claimed
EP-2111877-A1 Bioabsorbable surgical composition Tyco Healthcare Group LP (US) 2009-10-28 EP claimed
CN-114269848-B Composition for forming heat conductive material, heat conductive sheet, and device with heat conductive layer 富士胶片株式会社 2024-07-16 CN disclosed
CN-118317991-A Isocyanate composition and optical composition 韩华思路信(株) 2024-07-09 CN disclosed
CN-118215715-A Method for improving resin properties 博奇斯有限公司 2024-06-18 CN disclosed
CN-114846032-B Radical polymerizable resin composition and cured product thereof 株式会社力森诺科 2024-06-18 CN disclosed
WO-2024106985-A1 XYLENE DIISOCYANATE COMPOSITION AND PREPARATION METHOD THEREFOR 한화솔루션 주식회사 2024-05-23 WO disclosed
CN-115443296-B Diisocyanate composition and optical lens produced using the same 爱思开核心聚氨酯有限公司 2024-05-07 CN disclosed
CN-117715760-A Compositions and methods comprising chain transfer agents in absorbable photopolymerizable formulations 聚合-医药有限公司 2024-03-15 CN disclosed
EP-1263828-A1 COMPOSITIONS COMPRISING AN ISOCYANATE-FUNCTIONAL COMPOUND, AND ISOCYANATE-REACTIVE COMPOUND, AND A CO-CATALYST Akzo Nobel N.V. (NL) 2002-12-11 EP disclosed
US-20020032248-A1 Photoactivatable coating composition AKZO NOBEL N.V. (NL) 2002-03-14 US disclosed
EP-1177232-A1 COMPOSITION COMPRISING MERCAPTO-FUNCTIONAL COMPOUNDS Akzo Nobel N.V. (NL) 2002-02-06 EP disclosed
WO-2001092362-A1 PHOTOACTIVATABLE COATING COMPOSITION AKZO NOBEL N.V. (NL) 2001-12-06 WO disclosed
US-20010047071-A1 Compositions comprising an isocyanate-functional compound, an isocyanate-reactive compound, and a co-catalyst AKZO NOBEL N.V. (NL) 2001-11-29 US disclosed
WO-2001068736-A1 COMPOSITIONS COMPRISING AN ISOCYANATE-FUNCTIONAL COMPOUND, AND ISOCYANATE-REACTIVE COMPOUND, AND A CO-CATALYST AKZO NOBEL N.V. (NL) 2001-09-20 WO disclosed
WO-2000064959-A1 COMPOSITION COMPRISING MERCAPTO-FUNCTIONAL COMPOUNDS AKZO NOBEL N.V. (NL) 2000-11-02 WO disclosed