Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1061794 | 1.00 | LMNA (0.49) | LMNAALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL2968427 | 1.00 | LMNA (0.49) | LMNAALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL8040628 | 0.98 | ALDH1A1 (0.47) | LMNAALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL8040626 | 0.98 | ALDH1A1 (0.47) | LMNAALDH1A1SMN1; SMN2TP53MAPT | |
| Ammonia Solution, Strong SCHEMBL28025615 | 0.98 | ALDH1A1 (0.47) | LMNAALDH1A1SMN1; SMN2TP53MAPT | |
| Phosphine SCHEMBL27800452 | 0.93 | ALDH1A1 (0.44) | LMNAALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL8709766 | 0.86 | LMNA (0.47) | LMNAALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL8709763 | 0.86 | LMNA (0.47) | LMNAALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL2342911 | 0.86 | ALDH1A1 (0.50) | LMNAALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL4607473 | 0.86 | ALDH1A1 (0.50) | LMNAALDH1A1SMN1; SMN2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180179232-A1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-06-28 | — | — | US | disclosed |
| US-4356324-A | CHIRAL LIGANDS FOR RHODIUM HYDROGENATION CATALYSTS | DEGUSSA AKTIENGESELLSCHAFT, A GERMAN CORP. (DE) | 1982-10-26 | — | — | US | disclosed |
| EP-0031877-A1 | Optically active 1,2-Bis-(diphenylphosphino)-compounds, metal complexes containing them as chiral ligands and their use | Degussa Aktiengesellschaft (DE) | 1981-07-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179232-A1 | BORONIC ACID DERIVATIVES | BCL9, BCL9L, BCL6 | LMNA 1855/4885ALDH1A1 1217/4885SMN1; SMN2 2411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.