Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1061794 | 1.00 | LMNA (0.49) | LMNAALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL11249889 | 1.00 | LMNA (0.49) | LMNAALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL8040628 | 0.98 | ALDH1A1 (0.47) | LMNAALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL8040626 | 0.98 | ALDH1A1 (0.47) | LMNAALDH1A1SMN1; SMN2TP53MAPT | |
| Ammonia Solution, Strong SCHEMBL28025615 | 0.98 | ALDH1A1 (0.47) | LMNAALDH1A1SMN1; SMN2TP53MAPT | |
| Phosphine SCHEMBL27800452 | 0.93 | ALDH1A1 (0.44) | LMNAALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL8709766 | 0.86 | LMNA (0.47) | LMNAALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL8709763 | 0.86 | LMNA (0.47) | LMNAALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL2342911 | 0.86 | ALDH1A1 (0.50) | LMNAALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL4607473 | 0.86 | ALDH1A1 (0.50) | LMNAALDH1A1SMN1; SMN2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110196335-A | Biomarker relevant to renal function and its application method | 梅塔博隆股份有限公司 | 2019-09-03 | — | — | CN | claimed |
| CN-109715185-A | Water soluble and chemically stable glucagon peptides | 印第安纳大学研究及科技有限公司 | 2019-05-03 | — | — | CN | claimed |
| CN-109689079-A | Bovine fibroblast growth factor 21 and ketosis in dairy cattle | 伊兰科美国公司 | 2019-04-26 | — | — | CN | claimed |
| CN-108350025-A | additive system for protein PEGylation | 百时美施贵宝公司 | 2018-07-31 | — | — | CN | claimed |
| CN-104619349-B | Prostate specific membrane antigen antibody drug conjugates | AMBRX公司 | 2018-07-10 | — | — | CN | claimed |
| CN-107674121-A | Bovine somatotropin polypeptide and its purposes by modification | AMBRX 公司 | 2018-02-09 | — | — | CN | claimed |
| CN-107614010-A | It is bound to the antibody drug conjugates (ADC) of FLT3 albumen | 艾更斯司股份有限公司 | 2018-01-19 | — | — | CN | claimed |
| CN-104163864-B | Through modifying the polypeptides of FGF 21 and its purposes | AMBRX公司 | 2017-08-01 | — | — | CN | claimed |
| CN-101663046-B | modified FGF-21 polypeptides and uses thereof | AMBRX公司 | 2017-07-28 | — | — | CN | claimed |
| CN-106008699-A | Modified human plasma polypeptide or Fc scaffolds and their uses | AMBRX公司 | 2016-10-12 | — | — | CN | claimed |
| CN-102703446-A | Compositions of trna and uses thereof | AMBRX INC | 2012-10-03 | — | — | CN | claimed |
| CN-101087875-B | Compositions of aminoacyl-tRNA synthetases and uses thereof | AMBRX INC | 2012-08-22 | — | — | CN | claimed |
| CN-102459325-A | Gastrostatin receptor activated glucagon compounds | UNIV INDIANA RES & TECH CORP | 2012-05-16 | — | — | CN | claimed |
| CN-102325539-A | Amide based glucagon superfamily peptide prodrugs | UNIV INDIANA RES & TECH CORP | 2012-01-18 | — | — | CN | claimed |
| CN-102307905-A | Production of carrier-peptide conjugates using chemically reactive unnatural amino acids | SCRIPPS RESEARCH INST | 2012-01-04 | — | — | CN | claimed |
| CN-101983066-A | Ester-based peptide prodrugs | UNIV INDIANA RES & TECH CORP | 2011-03-02 | — | — | CN | claimed |
| CN-101384711-A | Non-natural amino acid polypeptides having modulated immunogenicity | AMBRX INC (US) | 2009-03-11 | — | — | CN | claimed |
| CN-101273140-A | tRNA compositions and uses thereof | AMBRX INC (US) | 2008-09-24 | — | — | CN | claimed |
| CN-101265298-A | Endothelium chalone mutant containing non-natural amino acid and derivatives thereof | UNIV CHINA PHARMA (CN) | 2008-09-17 | — | — | CN | claimed |
| CN-101087875-A | Compositions of aminoacyl-tRNA synthetases and uses thereof | AMBRX INC (US) | 2007-12-12 | — | — | CN | claimed |