Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250446 | 1.00 | GPR35 (0.50) | GPR35TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL3206927 | 0.92 | GPR35 (0.55) | GPR35TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL48360 | 0.87 | GPR35 (0.53) | GPR35TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL48361 | 0.87 | GPR35 (0.53) | GPR35TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL48359 | 0.85 | GPR35 (0.55) | GPR35TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL31694579 | 0.85 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL1652615 | 0.82 | GPR35 (0.51) | GPR35TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL17005575 | 0.82 | TSHR (0.51) | GPR35TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL2373772 | 0.82 | GPR35 (0.51) | GPR35TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL25331485 | 0.81 | TSHR (0.50) | GPR35TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4365018-A | SELF-EXPOSING, CHEMILUMINESCENCE | THE MEAD CORPORATION (US) | 1982-12-21 | — | — | US | disclosed |
| US-4233402-A | CHEMICAL ANALYSIS OF A BINDING PAIR OF LIGANDS AND ENZYMES BY LIGHT SIGNALS | SYVA COMPANY (US) | 1980-11-11 | — | — | US | disclosed |