Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252094 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8848886 | 0.81 | PLA2G7 (0.47) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8441573 | 0.81 | PLA2G7 (0.47) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9292212 | 0.80 | POLB (0.50) | SMN1; SMN2ALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL9292207 | 0.80 | POLB (0.50) | SMN1; SMN2ALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL23504933 | 0.78 | NPSR1 (0.50) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL1344772 | 0.78 | NPSR1 (0.50) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL8442853 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1CYP1A2MAPTNPC1 | |
| SCHEMBL1344768 | 0.78 | NPSR1 (0.50) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL10085282 | 0.76 | MAPT (0.42) | SMN1; SMN2ALDH1A1HPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327213-A | ANTIULCER AGENTS | ACF Chemiefarma VA (NL) | 1982-04-27 | — | — | US | disclosed |