SCHEMBL11252169

SCHEMBL11252169

CCC1CCC(C#N)(NC(=O)CCl)CC1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.35
RAB9A P51151 1/20 0.35
PAX8 Q06710 1/20 0.35
CTSS P25774 7/20 0.33
CTSK P43235 4/20 0.33
CTSC P53634 2/20 0.33
CTSL P07711 5/20 0.32
CTSB P07858 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11321743 0.85 CTSS (0.33) CTSSCTSKCTSCCTSLCTSB
SCHEMBL11259657 0.84 LMNA (0.42) NPC1RAB9APAX8CTSSCTSK
SCHEMBL24767282 0.83 CTSS (0.36) CTSSCTSKCTSCCTSLCTSB
SCHEMBL11247776 0.82 CTSL (0.35) NPC1RAB9APAX8CTSSCTSK
SCHEMBL11253656 0.79 NPC1 (0.49) NPC1RAB9APAX8TDP1ALDH1A1
SCHEMBL11250957 0.77 NPC1 (0.51) NPC1RAB9APAX8TDP1ALDH1A1
SCHEMBL11255307 0.77 NPC1 (0.51) NPC1RAB9APAX8TDP1ALDH1A1
SCHEMBL16358078 0.73 CTSS (0.46) CTSSCTSKCTSLCTSB
SCHEMBL15427227 0.71 CTSS (0.42) CTSSCTSKCTSCCTSLCTSB
SCHEMBL87370 0.69 CTSS (0.51) CTSSCTSKCTSLCTSBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4335053-A HERBICIDES STAUFFER CHEMICAL COMPANY (US) 1982-06-15 US disclosed
US-4288384-A N-Cyanoalkyl haloacetamides herbicidal antidotes STAUFFER CHEMICAL COMPANY (US) 1981-09-08 US disclosed