Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252696 | 0.81 | GPBAR1 (0.38) | MEN1KMT2AARMAPTALDH1A1 | |
| SCHEMBL11271112 | 0.79 | ALDH1A1 (0.44) | LIPEMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11268824 | 0.79 | KDR (0.44) | SMN1; SMN2NPSR1BRAF | |
| SCHEMBL11266692 | 0.78 | RXRA (0.47) | ARHTR2AKCNH2 | |
| Hydrochloric Acid SCHEMBL11727190 | 0.77 | KDR (0.43) | SMN1; SMN2NPSR1BRAF | |
| Hydrochloric Acid SCHEMBL11720486 | 0.76 | HDAC8 (0.41) | AR | |
| SCHEMBL9638977 | 0.73 | ALDH1A1 (0.44) | MAPTKDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL1773615 | 0.71 | MAOA (0.52) | MEN1KMT2ASTK39ARMAPT | |
| SCHEMBL3530293 | 0.71 | EGLN1 (0.38) | KMT2ASTK39AREGLN1MAPT | |
| SCHEMBL11307960 | 0.71 | SCN9A (0.49) | KMT2ASTK39EGLN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358611-A | FROM A PHENYLHYDRAZINE, A CHLOROFORMATE, PHOSGENE AND A SECONDARY AMINE | SHELL OIL COMPANY (US) | 1982-11-09 | — | — | US | disclosed |