Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252696 | 0.85 | GPBAR1 (0.38) | PGRARS1PR1HTR2AHTR2C | |
| SCHEMBL11253466 | 0.80 | RORC (0.48) | S1PR3IRAK4S1PR1 | |
| SCHEMBL11253129 | 0.78 | LIPE (0.39) | ARHTR2AKCNH2 | |
| Hydrochloric Acid SCHEMBL11720486 | 0.77 | HDAC8 (0.41) | PGRAR | |
| SCHEMBL11268824 | 0.77 | KDR (0.44) | S1PR1 | |
| Hydrochloric Acid SCHEMBL11727190 | 0.76 | KDR (0.43) | S1PR1 | |
| SCHEMBL11720549 | 0.73 | TP53 (0.50) | RXRARXRBRXRGARKCNH2 | |
| SCHEMBL17664021 | 0.72 | RXRA (0.53) | RXRARXRBRXRGS1PR3IRAK4 | |
| SCHEMBL403300 | 0.71 | RXRA (0.58) | RXRARXRBRXRGS1PR3S1PR1 | |
| SCHEMBL17386570 | 0.71 | RXRA (0.54) | RXRARXRBRXRGS1PR3S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358611-A | FROM A PHENYLHYDRAZINE, A CHLOROFORMATE, PHOSGENE AND A SECONDARY AMINE | SHELL OIL COMPANY (US) | 1982-11-09 | — | — | US | claimed |
| US-4358611-A | FROM A PHENYLHYDRAZINE, A CHLOROFORMATE, PHOSGENE AND A SECONDARY AMINE | SHELL OIL COMPANY (US) | 1982-11-09 | — | — | US | disclosed |
| US-4099956-A | Herbicidal semicarbazones | SHELL OIL COMPANY (US) | 1978-07-11 | — | — | US | disclosed |