Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 11/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253114 | 0.89 | AMY1A (0.47) | AMY1AKDM4EALDH1A1TP53MAPT | |
| SCHEMBL11262531 | 0.88 | AMY1A (0.41) | AMY1AHRH4NPBWR1MEN1KMT2A | |
| SCHEMBL11259880 | 0.87 | AMY1A (0.51) | AMY1ANPBWR1MEN1MAPTKMT2A | |
| SCHEMBL11264095 | 0.85 | AMY1A (0.34) | AMY1APTGESKDM4EALDH1A1MAPK1 | |
| SCHEMBL11255428 | 0.84 | ALDH1A1 (0.44) | AMY1AKDM4EALDH1A1HPGD | |
| SCHEMBL11266547 | 0.83 | RHEB (0.31) | — | |
| Hydrochloric Acid SCHEMBL11264419 | 0.79 | PDE5A (0.43) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL11261992 | 0.76 | METAP2 (0.33) | MAPT | |
| SCHEMBL11253305 | 0.72 | NPC1 (0.48) | AMY1AKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL11251140 | 0.72 | ALDH1A1 (0.40) | AMY1AKDM4EMEN1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329459-A | ENDOPEROXIDE CYCLOXGENASE INHIBITORS | THE UPJOHN COMPANY (US) | 1982-05-11 | — | — | US | claimed |
| US-4329459-A | ENDOPEROXIDE CYCLOXGENASE INHIBITORS | THE UPJOHN COMPANY (US) | 1982-05-11 | — | — | US | disclosed |