Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 8/20 | 0.51 |
| ▸ | GUSB | P08236 | 5/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 2/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | CBFB | Q13951 | 1/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262531 | 0.90 | AMY1A (0.41) | AMY1ANPC1RAB9ANPBWR1MEN1 | |
| SCHEMBL11262388 | 0.87 | AMY1A (0.37) | AMY1ANPBWR1MEN1MAPTKMT2A | |
| SCHEMBL11253114 | 0.84 | AMY1A (0.47) | AMY1ANPC1RAB9AMAPT | |
| SCHEMBL11255428 | 0.82 | ALDH1A1 (0.44) | AMY1ANPC1RAB9AMETAP1METAP2 | |
| SCHEMBL11266547 | 0.79 | RHEB (0.31) | — | |
| SCHEMBL11264095 | 0.79 | AMY1A (0.34) | AMY1ANPC1RAB9ATDP1 | |
| Hydrochloric Acid SCHEMBL11264419 | 0.77 | PDE5A (0.43) | METAP1METAP2MEN1KMT2A | |
| SCHEMBL11261992 | 0.76 | METAP2 (0.33) | NPC1RAB9AMETAP1METAP2MAPT | |
| SCHEMBL17269667 | 0.72 | AKT1 (0.41) | — | |
| SCHEMBL11251140 | 0.70 | ALDH1A1 (0.40) | AMY1ANPC1RAB9AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329459-A | ENDOPEROXIDE CYCLOXGENASE INHIBITORS | THE UPJOHN COMPANY (US) | 1982-05-11 | — | — | US | claimed |
| US-4329459-A | ENDOPEROXIDE CYCLOXGENASE INHIBITORS | THE UPJOHN COMPANY (US) | 1982-05-11 | — | — | US | disclosed |