Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | PLEC | Q15149 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260264 | 0.89 | ALDH1A1 (0.50) | KMT2AMEN1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL11253756 | 0.86 | MAPT (0.45) | KMT2AMEN1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL11259763 | 0.86 | ALDH1A1 (0.59) | KMT2AMEN1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL28277649 | 0.72 | MAPT (0.67) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL11263016 | 0.71 | ALDH1A1 (0.42) | KMT2AMEN1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL11268463 | 0.71 | CASP3 (0.48) | KMT2AMEN1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL27987747 | 0.70 | MEN1 (0.54) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11318312 | 0.69 | LMNA (0.49) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28639448 | 0.69 | ALDH1A1 (0.83) | KMT2AMEN1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL11263457 | 0.68 | CASP3 (0.45) | ALDH1A1KDM4EL3MBTL1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353734-A | PRE- AND POSTEMERGENCE | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1982-10-12 | — | — | US | claimed |