Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 8/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SPR | P35270 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258337 | 0.88 | PLA2G2A (0.55) | PLA2G2AGAALMNAMAPTPKM | |
| SCHEMBL11264662 | 0.88 | PLA2G2A (0.44) | PLA2G2AGAALMNAMAPTPKM | |
| SCHEMBL11258878 | 0.85 | PLA2G2A (0.47) | PLA2G2AGAALMNAMAPTPKM | |
| SCHEMBL11252321 | 0.84 | SPR (0.53) | PLA2G2AGAALMNAMAPTPKM | |
| SCHEMBL11374544 | 0.83 | L3MBTL1 (0.52) | PLA2G2AGAALMNAMAPTPKM | |
| SCHEMBL2001561 | 0.80 | PLA2G2A (0.64) | PLA2G2AGAALMNAMAPTPKM | |
| SCHEMBL27360541 | 0.78 | PLA2G2A (0.79) | PLA2G2A | |
| SCHEMBL11257449 | 0.78 | PLA2G2A (0.52) | PLA2G2AMEN1KMT2APOLB | |
| SCHEMBL9734021 | 0.77 | PLA2G2A (0.70) | PLA2G2AGAALMNAMAPTPKM | |
| SCHEMBL27407027 | 0.76 | PLA2G2A (0.59) | PLA2G2AGAALMNAMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015523-B1 | INDOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE FOR MEDICAMENTS | Dr. Karl Thomae GmbH (DE) | 1982-10-13 | — | — | EP | disclosed |
| US-4343811-A | ATHEROSCLEROSIS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-10 | — | — | US | disclosed |
| EP-0015523-A1 | Indole derivatives, their preparation and their use for medicaments | Dr. Karl Thomae GmbH (DE) | 1980-09-17 | — | — | EP | disclosed |