Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254007 | 0.88 | PLA2G2A (0.54) | PLA2G2AKDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL11257678 | 0.87 | PLA2G2A (0.45) | PLA2G2AKDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL3854952 | 0.77 | PLA2G2A (0.60) | PLA2G2AKDM4ELMNAALDH1A1GAA | |
| SCHEMBL11374544 | 0.77 | L3MBTL1 (0.52) | PLA2G2AKDM4ELMNAGAAMAPT | |
| SCHEMBL2001561 | 0.76 | PLA2G2A (0.64) | PLA2G2AKDM4ELMNAALDH1A1POLB | |
| SCHEMBL11264662 | 0.76 | PLA2G2A (0.44) | PLA2G2AKDM4ELMNAALDH1A1GAA | |
| SCHEMBL11260099 | 0.75 | PPARG (0.47) | PLA2G2AKDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL7699338 | 0.75 | PLA2G2A (0.73) | PLA2G2AKDM4ELMNAALDH1A1GAA | |
| SCHEMBL11258878 | 0.74 | PLA2G2A (0.47) | PLA2G2AKDM4ELMNAALDH1A1POLB | |
| SCHEMBL27360541 | 0.74 | PLA2G2A (0.79) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015523-B1 | INDOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE FOR MEDICAMENTS | Dr. Karl Thomae GmbH (DE) | 1982-10-13 | — | — | EP | disclosed |
| US-4343811-A | ATHEROSCLEROSIS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-10 | — | — | US | disclosed |
| EP-0015523-A1 | Indole derivatives, their preparation and their use for medicaments | Dr. Karl Thomae GmbH (DE) | 1980-09-17 | — | — | EP | disclosed |