Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HRH1 | P35367 | 3/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | DRD5 | P21918 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257034 | 0.99 | L3MBTL1 (0.72) | L3MBTL1CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL11265539 | 0.88 | KCNH2 (0.66) | L3MBTL1CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL11255661 | 0.86 | ALDH1A1 (0.62) | L3MBTL1CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL11253990 | 0.86 | L3MBTL1 (0.61) | L3MBTL1CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL11253167 | 0.85 | L3MBTL1 (0.81) | L3MBTL1CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL11251607 | 0.85 | HRH1 (0.71) | L3MBTL1CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL11257123 | 0.85 | L3MBTL1 (0.60) | L3MBTL1CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL11248323 | 0.84 | L3MBTL1 (0.74) | L3MBTL1CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL11270477 | 0.84 | HRH1 (0.71) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11260259 | 0.84 | HRH3 (0.69) | L3MBTL1CYP1A2CYP2D6CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323568-A | INHIBIT PLATELET AGGREGATION | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| EP-0001759-B1 | (OMEGA-AMINOALKOXY) BIBENZYLS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE SUBSTANCES | MITSUBISHI KASEI CORPORATION (JP) | 1981-12-30 | — | — | EP | disclosed |
| US-4220603-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1980-09-02 | — | — | US | disclosed |
| EP-0001759-A1 | (Omega-aminoalkoxy) bibenzyls, processes for their preparation and pharmaceutical compositions containing these substances | MITSUBISHI KASEI CORPORATION (JP) | 1979-05-16 | — | — | EP | disclosed |