Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246032 | 0.87 | HRH3 (0.60) | ALDH1A1LMNAHRH3MEN1MAPK1 | |
| SCHEMBL11254277 | 0.86 | L3MBTL1 (0.74) | ALDH1A1MEN1KMT2AKCNH2CYP2D6 | |
| SCHEMBL11260340 | 0.85 | KCNH2 (0.54) | ALDH1A1LMNAHRH3MEN1MAPK1 | |
| SCHEMBL11257034 | 0.85 | L3MBTL1 (0.72) | ALDH1A1HRH3MEN1KMT2AKCNH2 | |
| SCHEMBL11252854 | 0.84 | KCNH2 (0.53) | ALDH1A1LMNAHRH3MEN1MAPK1 | |
| SCHEMBL11251231 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNAHRH3MEN1MAPK1 | |
| SCHEMBL11265539 | 0.83 | KCNH2 (0.66) | ALDH1A1LMNAMEN1KMT2AKCNH2 | |
| SCHEMBL11253964 | 0.83 | SIGMAR1 (0.61) | ALDH1A1LMNAHRH3MEN1MAPK1 | |
| SCHEMBL17117585 | 0.80 | KCNH2 (0.70) | ALDH1A1HRH3KCNH2 | |
| SCHEMBL11255822 | 0.79 | KDM4E (0.59) | ALDH1A1LMNAHRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323568-A | INHIBIT PLATELET AGGREGATION | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| EP-0001759-B1 | (OMEGA-AMINOALKOXY) BIBENZYLS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE SUBSTANCES | MITSUBISHI KASEI CORPORATION (JP) | 1981-12-30 | — | — | EP | disclosed |
| US-4220603-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1980-09-02 | — | — | US | disclosed |
| EP-0001759-A1 | (Omega-aminoalkoxy) bibenzyls, processes for their preparation and pharmaceutical compositions containing these substances | MITSUBISHI KASEI CORPORATION (JP) | 1979-05-16 | — | — | EP | disclosed |