Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.30 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | HTR7 | P34969 | 2/20 | 0.30 |
| ▸ | HTR6 | P50406 | 2/20 | 0.30 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9373101 | 0.93 | FLT3 (0.37) | FLT3TYRO3MERTKGAS6SIGMAR1 | |
| SCHEMBL9645849 | 0.92 | FLT3 (0.35) | FLT3TYRO3MERTKGAS6KMT2A | |
| SCHEMBL28706950 | 0.90 | CA12 (0.31) | FLT3TYRO3MERTKGAS6KMT2A | |
| SCHEMBL3141095 | 0.87 | KMT2A (0.45) | FLT3TYRO3MERTKGAS6KMT2A | |
| SCHEMBL7058617 | 0.86 | — | — | |
| SCHEMBL714018 | 0.85 | KMT2A (0.43) | FLT3TYRO3MERTKGAS6KMT2A | |
| SCHEMBL698650 | 0.83 | KMT2A (0.40) | FLT3TYRO3MERTKGAS6KMT2A | |
| SCHEMBL9368674 | 0.82 | ESR1 (0.35) | FLT3TYRO3MERTKGAS6 | |
| SCHEMBL3169436 | 0.81 | SIGMAR1 (0.41) | SIGMAR1RAD52 | |
| SCHEMBL5648885 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322337-A | PHOTOSTABILITY | CIBA-GEIGY CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| EP-0014683-B1 | POLYALKYLPIPERIDINE DERIVATIVES OF S-TRIAZINES, THEIR USE AS STABILIZERS FOR POLYMERS AND POLYMER COMPOSITIONS STABILIZED WITH THESE COMPOUNDS | CIBA-GEIGY AG (CH) | 1981-12-23 | — | — | EP | disclosed |
| US-4288593-A | PHOTOSTABILIZERS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |