SCHEMBL698650

SCHEMBL698650

CN1C(C)(C)CC(CCCCNc2nc(Cl)nc(Cl)n2)CC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.40
LMNA P02545 2/20 0.33
FLT3 P36888 1/20 0.33
TYRO3 Q06418 1/20 0.33
MERTK Q12866 1/20 0.33
GAS6 Q14393 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
NR1I2 O75469 1/20 0.30
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL714018 0.97 KMT2A (0.43) KMT2ALMNAFLT3TYRO3MERTK
SCHEMBL3141095 0.96 KMT2A (0.45) KMT2ALMNAFLT3TYRO3MERTK
SCHEMBL9645849 0.90 FLT3 (0.35) KMT2AFLT3TYRO3MERTKGAS6
SCHEMBL9373101 0.89 FLT3 (0.37) KMT2AFLT3TYRO3MERTKGAS6
SCHEMBL27717304 0.86 FLT3 (0.36) KMT2AFLT3TYRO3MERTKGAS6
SCHEMBL7976903 0.86 KMT2A (0.37) KMT2ALMNA
SCHEMBL2022080 0.85 KMT2A (0.45) KMT2ALMNANR1I2AHR
SCHEMBL7458930 0.83 KMT2A (0.40) KMT2ALMNANR1I2AHR
SCHEMBL692772 0.83 KMT2A (0.40) KMT2ALMNASMN1; SMN2NR1I2AHR
SCHEMBL11255263 0.83 FLT3 (0.34) KMT2AFLT3TYRO3MERTKGAS6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024117646-A1 THERMOPLASTIC RESIN COMPOSITION FOR LIGHT-EMITTING DIODE REFLECTOR AND MOLDED PRODUCT COMPRISING SAME 롯데케미칼 주식회사 2024-06-06 WO claimed
EP-3565861-B1 PHOTOCURABLE HARDCOAT COMPOSITIONS, METHODS, AND ARTICLES DERIVED THEREFROM BASF SE (DE) 2023-06-21 EP claimed
US-11623979-B2 Stabilized polyolefin compositions comprising benzofuranones and hindered amine light stabilizers BASF SE (DE) 2023-04-11 US claimed
US-20220282064-A1 STABILIZER COMPOSITION BASF SE (DE) 2022-09-08 US claimed
CN-110352223-B Coating composition with covalently bound UV absorber 巴斯夫欧洲公司 2022-08-02 CN claimed
EP-3841166-B1 STABILIZED ROTOMOLDED POLYOLEFIN BASF SE (DE) 2022-07-20 EP claimed
EP-4004099-A1 STABILIZER COMPOSITION BASF SE (DE) 2022-06-01 EP claimed
CN-114144464-A Stabilizer composition 巴斯夫欧洲公司 2022-03-04 CN claimed
US-11254837-B2 Coating compositions having covalently bound ultraviolet absorbers BASF SE 2022-02-22 US claimed
EP-3941970-A1 UV CURABLE COMPOSITIONS FOR DIRT PICK-UP RESISTANCE BASF SE (DE) 2022-01-26 EP claimed
US-9410057-B2 Coated carbon fiber reinforced plastic parts BASF SE (DE) 2016-08-09 US claimed
EP-3049464-A2 POLYOLEFIN COMPOSITIONS FOR BUILDING MATERIALS BASF SE (DE) 2016-08-03 EP claimed
US-20160009952-A1 Coated carbon fiber reinforced plastic parts BASF SE (DE) 2016-01-14 US claimed
EP-1888686-B1 SCRATCH RESISTANT POLYOLEFINS BASF SE (DE) 2013-01-23 EP claimed
US-8357324-B2 Rotomolding process for polyethylene articles BASF SE (DE) 2013-01-22 US claimed
US-20100327487-A1 Rotomolding Process for Polyethylene Articles BASF PERFORMANCE PRODUCTS LLC (US) 2010-12-30 US claimed
EP-1888686-A1 SCRATCH RESISTANT POLYOLEFINS Ciba Specialty Chemicals Holding Inc. (CH) 2008-02-20 EP claimed
US-20070151143-A1 Stabilized biodiesel fuel compositions CIBA SPECIALTY CHEMICALS CORP. 2007-07-05 US claimed
WO-2006131455-A1 SCRATCH RESISTANT POLYOLEFINS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-12-14 WO claimed
US-20060276571-A1 Scratch resistant polyolefins CIBA SPECIALTY CHEMICALS CORP. 2006-12-07 US claimed