Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 4/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255307 | 0.76 | NPC1 (0.51) | HPGDNPC1RAB9APAX8CTDSP1 | |
| SCHEMBL11253284 | 0.76 | NPC1 (0.45) | HPGDNPC1RAB9APAX8CTDSP1 | |
| SCHEMBL11250957 | 0.76 | NPC1 (0.51) | HPGDNPC1RAB9APAX8CTDSP1 | |
| SCHEMBL11253656 | 0.74 | NPC1 (0.49) | HPGDNPC1RAB9APAX8CTDSP1 | |
| SCHEMBL27991912 | 0.74 | KDM4E (0.45) | HPGDNPC1RAB9APAX8CTDSP1 | |
| SCHEMBL6836051 | 0.72 | CTSL (0.53) | HPGDCTSLCTSSCTSBNPC1 | |
| SCHEMBL16358078 | 0.70 | CTSS (0.46) | EPHX1CTSLCTSSCTSB | |
| SCHEMBL23795558 | 0.70 | CTSB (0.42) | KMT2ACTSLCTSSCTSBNPC1 | |
| SCHEMBL3234020 | 0.69 | CTSS (0.50) | CTSLCTSSCTSB | |
| SCHEMBL3831093 | 0.69 | CTSL (0.45) | KMT2ACTSLCTSSCTSBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2020413-A1 | Oxaspirocyclical spiro-substituted tetram and tetron acid derivatives | Bayer CropScience AG (DE) | 2009-02-04 | — | — | EP | disclosed |