Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261511 | 0.82 | MAPT (0.46) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11264349 | 0.81 | MAPT (0.45) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL11261507 | 0.80 | CCNE1 (0.36) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11264345 | 0.79 | CCNE1 (0.35) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL11260982 | 0.79 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL28144507 | 0.72 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL4861743 | 0.68 | GAA (0.62) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL5904228 | 0.67 | POLB (0.68) | LMNAMEN1KMT2APOLBNPC1 | |
| SCHEMBL11268232 | 0.67 | NPC1 (0.53) | ALDH1A1LMNAMAPTCASP2KDM4E | |
| SCHEMBL21589413 | 0.67 | NPC1 (0.65) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |