Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 4/20 | 0.41 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 2/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253114 | 0.86 | AMY1A (0.47) | ALDH1A1KDM4EHPGDPKMNPC1 | |
| SCHEMBL11262388 | 0.84 | AMY1A (0.37) | ALDH1A1KDM4EHPGDAMY1A | |
| SCHEMBL11252873 | 0.84 | PDE5A (0.48) | ALDH1A1KDM4EHPGDPKMNPC1 | |
| SCHEMBL11262531 | 0.83 | AMY1A (0.41) | NPC1RAB9AAMY1A | |
| SCHEMBL11259880 | 0.82 | AMY1A (0.51) | NPC1RAB9AMETAP1METAP2HPSE | |
| SCHEMBL11266547 | 0.79 | RHEB (0.31) | — | |
| Hydrochloric Acid SCHEMBL11264419 | 0.78 | PDE5A (0.43) | ALDH1A1KDM4EHPGDPDE5APDE3B | |
| SCHEMBL11261992 | 0.78 | METAP2 (0.33) | NPC1RAB9AMETAP1METAP2 | |
| SCHEMBL11264095 | 0.77 | AMY1A (0.34) | ALDH1A1KDM4ENPC1RAB9AAMY1A | |
| SCHEMBL11256562 | 0.75 | PDE5A (0.38) | ALDH1A1KDM4EHPGDPKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329459-A | ENDOPEROXIDE CYCLOXGENASE INHIBITORS | THE UPJOHN COMPANY (US) | 1982-05-11 | — | — | US | claimed |
| US-4329459-A | ENDOPEROXIDE CYCLOXGENASE INHIBITORS | THE UPJOHN COMPANY (US) | 1982-05-11 | — | — | US | disclosed |