Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ACP1 | P24666 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19844512 | 0.85 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL26807831 | 0.82 | ALDH1A1 (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL11255758 | 0.81 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL11263726 | 0.80 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL18163646 | 0.79 | DYRK1A (0.69) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL11253925 | 0.79 | ALDH1A1 (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL18154264 | 0.78 | DYRK1A (0.67) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL29699065 | 0.78 | DYRK1A (0.67) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL11258414 | 0.77 | CASP2 (0.64) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL11256907 | 0.77 | MGLL (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |